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LNPs incorporating pSar instead of PEG lipid showed elevated mRNA expression levels in the spleen, with a tendency for increased spleen accumulation as their size diminished [236]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Aquilina J.A., Benesch J.L.P., Ding L.L., Yaron O., Horwitz J., Robinson C.V