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In contrast, Th2 (CD4 + IL-4 + ) and Treg cells (CD4 + Foxp3 + ), known to play critical roles counteracting inflammation in arthritis 19,20 , were increased only in the late stages of arthritis (Supplementary Fig

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Like warfarin, the most efficient reduction pathways led to alcohol 2 and in the case of rac -4′-hydroxywarfarin, the minor pathway for alcohol 1 was not even measurable