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After the washout period, participants were asked to apply cysteamine cream (5% cysteamine hydrochloride) once daily at night on unwashed skin or 1 hour after washing, initially for 15 minutes, gradually duration was increased to 30 minutes as per protocols in previous studies[5] followed by rinsing with water due to its offensive odor, over 6 weeks with SPF 30+ sunscreen use during the day

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