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In southeastern Asia, raw fish spicy salad and fermented fish are often consumed (62, 67)

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Glutamate (Glu) is an important excitatory amino acid neurotransmitter, with the highest content in brain tissue, released by about 3% of synapses, and acts on postsynaptic membrane receptors, mainly the N-methyl-D-aspartate receptor subtype (NMDAR), to exert excitatory regulatory effects