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However, the concrete metabolic response of ROS is unclear

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We hypothesize that osmotic stress and oxidative stress interact in a mutually amplifying loop during vitrification/thawing of oocytes, reducing osmotic stress with organic osmolytes or mitigating osmotic and oxidative stresses with physiological antioxidant and organic osmolytes together could enhance the developmental competency of vitrified porcine oocytes comparably