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Through this mechanism, sinusoidal endothelial cells are protected from hypoxia-reoxygenation damage, indirectly preventing hepatocyte injury via paracrine effects of sinusoidal endothelial cells (Noguchi et al., 2021)

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In this study, groups with higher GGT levels showed dose-dependent elevations in all-cause mortality and cardiovascular disease when adjusted for age, sex, body mass index (BMI), blood pressure, alcohol consumption, and smoking