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This analysis pooled results from trials of participants with mild cognitive impairment (6 trials) and trials of participants without cognitive impairment (15 trials)

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In some papers, a vitamin B 12 concentration of 150–350 pmol/L is defined as the “grey zone”, and in such cases the introduction of additional markers, namely holotranscobalamin II (holoTC II) methylmalonic acid (MMA) and homocystein (Hcy), might solve the problem [17,62,63]