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15 Another study showed that disulfiram (DSF)/Cu significantly impaired mitochondrial homeostasis, increased the free iron pool, and enhanced lipid peroxidation, leading to ferroptotic cell death

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P-coumaric acid is negatively correlated with liver injury parameters in patients with cholestatic liver disease, directly binds NADPH oxidase 2, and inhibits reactive oxygen species production in hepatocytes, thereby preventing hepatocyte death and liver injury