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In vivo , intra-articular injection of FN-CNPs in DMM mice slows OA progression and preserves cartilage integrity by modulating ROS levels, antioxidant defense, and lipid metabolism

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The pH dependence of nanozymes may be attributed to differences in redox reactivity and the stability of nanozymes, substrates, and products at varying pH levels as well as their interactions, such as substrate adsorption and product desorption, which jointly influence the overall pH dependence of nanozymes 150