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Regarding efficacy, in the 137 analyzed patients, the change from baseline to the end of observation in Visual Analogue Scale score (VAS) was statistically significant, ranging from 75.9 ± 1.56 to 51.9 ± 1.99 ( p 40 according to the VAS score (Visual Analogue Scale 0–100), who, between 2017 and 2022, were prescribed ALC, regardless of the concomitant pharmacological FMS therapy (add-on treatment)