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However, its potential as a CoV vaccine target was largely undermined by early studies of SARS-CoV showing that vaccines expressing N protein did not provide protection and, on the contrary, enhanced infection-induced pneumonia via increased pulmonary eosinophil infiltration and T H 2 cell-biased responses 39,41 , causing ERD

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Ein weiterer praktischer Pluspunkt der oralen Gabe ist die deutlich niedrigere Hürde: keine Nadeln, keine Injektionstechnik, kein Risiko lokaler Injektionsreaktionen