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Disease-related complications include: Strictures and bowel obstruction (mainly in Crohn’s) Fistulas and abscesses (mainly in Crohn’s, including perianal disease) Severe flares requiring hospital admission Toxic megacolon (a rare but serious complication of severe ulcerative colitis) Anaemia and nutrient deficiencies Bone thinning (osteopenia and osteoporosis) Increased risk of blood clots, especially during flares Colorectal cancer with long-standing colonic disease Extraintestinal complications affecting joints, eyes, skin, and liver Medication-related risks vary by drug

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S., Erickson, B