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Unlike compounds such as vitamin E or beta-carotene, AST readily crosses the blood–brain barrier and acts across both hydrophilic and lipophilic environments, enabling broad neuroprotective effects

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The present review aims to elucidate the mechanisms by which copper ions are involved in cardiovascular diseases, summarize the impact of copper ion abnormalities on cardiovascular diseases and potential therapeutic approaches, and investigate whether modulating copper ion levels can ameliorate cardiovascular diseases

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