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Both fall within the range that studies show can be effectively delivered intranasally, though the smaller BPC-157 may achieve somewhat higher bioavailability through this route

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The depletion of zinc observed in individuals with diabetes mellitus is primarily attributed to two key mechanisms: (1) impaired intestinal absorption of zinc (diabetes-associated gastrointestinal changes and alterations in zinc transport mechanisms can lead to reduced intestinal absorption of this essential micronutrient) and (2) increased urinary excretion of zinc (hyperglycemia and associated metabolic disturbances in diabetes can result in increased urinary loss of zinc, further exacerbating the deficiency) [4]