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In terms of the role of butyrate in renal ischemia reperfusion injury, it has been found that rats pre-treated with butyrate (300 mg/kg body weight, IV injection) followed by kidney ischemia reperfusion (30 min ischemia/24 h reperfusion) exhibited amelioration of kidney function and histological damage when compared with rats that were not pre-treated with sodium butyrate [43]

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