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In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma

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While muscle insulin resistance often precedes hepatic insulin resistance, diets that are high in fat have been shown to cause hepatic insulin resistance without muscle insulin resistance by blocking insulin-stimulated AKT phosphorylation in the liver