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Core Clock Genes/Proteins and Transcription‒Translation Feedback Loops In mammalian cells, the circadian rhythm is controlled by a core group of clock genes, including brain and muscle ARNT‐like protein‐1 (Bmal1), circadian locomotor output cycles (Clock), Period (Per), Cryptochrome (Cry), REV‐ERB, and retinoid orphan nuclear receptor (ROR) [18, 19]

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4 ml toluene was added to each cooled sample