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Although not clearly established, vitamin B12 level at 200 ng/L would be considered sensitive in diagnosing patients with such deficiency at 97% [26]

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These approaches include either targeting all β -coronaviruses, targeting a subset of these viruses (such as sarbecoviruses), or even targeting a single species with the aim of developing a pan-variant or “variant-proof” vaccine for SARS-CoV-2 (Table 1)