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We present novel findings showing that BH 4 supplementation, through treatment with its precursor sepiapterin, is neuroprotective in the retina during ischaemic hypoxia by increasing NO and decreasing nitro-oxidative species with normalization of the cellular redox state

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[DOI] [PMC free article] [PubMed] [Google Scholar] Long AN, Owens K, Schlappal AE, Kristian T, Fishman PS, Schuh RA