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You may not be a good candidate for the treatment if you: Have a preexisting, chronic health condition like cardiovascular or thyroid issues

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Although often described clinically as a form of “negative chorea”, it reflects a distinct and incompletely understood pathophysiological substrate: impaired sustained output from basal ganglia–thalamocortical circuits driven by progressive degeneration of D1- and D2-receptor-expressing MSNs, and further exacerbated by altered skeletal muscle excitability [133,134]