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Overall, due to good safety and tolerability profiles, our findings make NFX88 an attractive therapeutic option, as a second-line treatment, for SCI-related pain, because many current options are limited by a lack of efficacy or the presence of severe side effects

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SIRT1/FOXO1 axis-mediated hippocampal angiogenesis is involved in the antidepressant effect of chaihu shugan san