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SARS-CoV-2 Spike Protein Induces IL-18-Mediated Cardiopulmonary Inflammation via Reduced Mitophagy

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As deduced from an X-ray crystallographic analysis of 43 in complex with ERAP2 it was concluded that the three first specificity pockets of the enzyme was of particular importance for binding to the enzyme (Zervoudi et al., 2013)