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The use of high concentrations of curcumin makes sense only in anti-cancer or anti-microbial therapies such as PDT, when selectivity can be achieved by using nanocarriers or applying light that reaches only the affected areas

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There's no well-established list of major drug interactions for healthy adults at standard doses, but anyone on regular medication, especially chemotherapy, should still confirm with their doctor first, since antioxidant supplements can theoretically interact with certain treatments

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