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With the finale of K-drama Perfect Crown having aired just a few days ago, IU is once again back in the spotlight, with audiences still talking about her fair, luminous on-screen complexion.

However, hyperglycemia can induce a significant increase in vascular permeability via downregulating vascular endothelial-cadherin, which is an important adherent junction protein that maintains cell polarity and integrity (Li et al., 2019)

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We remind you that night time is the period with the most exuberant metabolism