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While TBI induction decreased the expression (0 fold) in rats in Group II

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Hydroxyl radical ( • OH) is taken into account as the most potent oxidant which, owing to its short half-life, very positive redox potential (close to +2 V) and high affinity for biomolecules, non-selectively oxidize DNA, proteins, lipids, amino acids, sugars, and metals, leading to damage or genetic instability