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Moreover, important signaling complexes associate with the outer lysosomal surface, particularly the master growth regulator, mechanistic Target of Rapamycin Complex 1 (mTORC1) kinase, which, upon integrating nutrients, growth factor and energy signals through its association with the lysosomal membrane, triggers signals that regulate the balance between anabolism and catabolism [5, 6]

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Harlan Teklad, Indianapolis, IN) for 8 weeks, keeping the GlyNAC supplemented diet isocaloric and isonitrogenous to the regular diet