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The TLD shares homology with the central domain of transcription factor IIS but lacks the ability to rescue backtracked Pol II by stimulating RNA cleavage, which is conferred by TFIIS domain III 39

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Folate (Vitamin B9) and folic acid from our diet undergoes a series of chemical reactions known as the folate cycle , which produces the active form of folate known as 5-methyltetrahydrofolate ( 5-methyl-THF )