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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Bowen R.A., Drake S.K., Vanjani R., Huey E.D., Grafman J., Horne M.K., III Markedly increased vitamin B12 concentrations attributable to IgG-IgM-vitamin B12 immune complexes

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The robust prevention, correction and repair activities of DNA polymerase keeps errors in replication at a low frequency of 1 per 10 −8 , while the proof-reading mechanisms of RNA polymerase allow a transcription error rate of about 1 in 10 −5