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These effects are particularly documented in preclinical models involving poorly vascularized tissues such as tendons and myotendinous junctions

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FIGURE 3 PEROXIREDOXIN–THIOREDOXIN REDOX CYCLE Peroxiredoxins constitute a family of thiol-specific peroxidases that rely on thioredoxins (Trxs) as the hydrogen donor for the reduction of H 2 O 2 and lipid hydroperoxides ( 2 O 2 produced by the mitochondrial respiratory chain