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The peptide significantly reduces pro-inflammatory cytokines including TNF-alpha, IL-1β, and IL-6, which are consistently elevated in fibromyalgia patients

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NGRA aims to conduct safety assessments that are “human-relevant, exposure-led, hypothesis-driven and designed to prevent harm” ( in vitro bioactivity at human-relevant concentrations and, consequently, adverse health effects, in lieu of replicating apical endpoints that would traditionally be obtained using high-dose animal studies (Thomas et al., 2019)