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The extensive literature on preclinical and clinical (including a large number of phase 3 clinical trials) studies of pharmacological modulation of HIF pathways is contrasted by comparably small, heterogeneous and difficult‐to‐compare pieces of evidence from studies on health effects of controlled hypoxia exposures, the main focus of the present review

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In principle, one would expect that the binding of C1q (a protein of molecular mass ~400–450 kDa) to nAb bound to virions would enhance neutralization by increasing steric hindrance of viral attachment to or fusion with host cell membrane (Fig