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Indeed, there is still a significant debate within the scientific community about the specific cut-off values that should be applied to define a low vitamin B12 status and about the definition of the best biomarker or combination of biomarkers to assess vitamin B12 status[1,12]

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Laboratories buying NAD+ in the UK typically use it as a defined cofactor in oxidoreductase assays and in sirtuin, PARP and mitochondrial bioenergetics work