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Senolytic agents include natural compounds such as quercetin 13 or fisetin 14 , β-galactosidase-activated nanoparticles and prodrugs 15,16,17 or compounds that target different vulnerabilities of senescent cells, such as HSP90 inhibitors 18 , cardiac glycosides 19,20 or NMT inhibitors 21

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doi: 10.1016/j.jvs.2012.11.090 102