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Peripheral inflammatory responses drive intracerebral inflammation via multiple routes, activating microglia and astrocytes to secrete pro-inflammatory mediators such as IL-1, IL-6, and TNF- (Mazarati et al., 2010

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[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Stratikopoulos E., Szabolcs M., Dragatsis I., Klinakis A., Efstratiadis A