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Combined therapy with a low dose (75 mg/kg) of diazoxide and the alkylating agents melphalan or N-(2-chloroethyl)-N-nitrosocarbamoyl (CNC)-omega-lysine increased the therapeutic efficacy of both cytostatics up to twofold in the MNU-induced rat mammary carcinoma

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The column temperature and tray temperature were set to 40°C and 4°C, respectively