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The excess iron is transported to the extracellular space through the iron transporter protein, or stored in ferritin and reacted with intracellular H 2 O 2 to generate highly active hydroxyl radicals (•OH) under slightly acidic conditions, which is known as the Fenton reaction (Fe 2+ + H 2 O 2 →Fe 3+ + OH − +·OH)

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[DOI] [PubMed] [Google Scholar] 77.Su N, Wu Q, Liu Y, Cai J, Shen W, Xia K, Cui J