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While the present study demonstrated significant increases in L-arginine levels ImmediatePEX (MD: 30.4 nmol/L) and 30minPEX (MD: 24.9 nmol/L) with SPB supplementation, there were no significant increases in vessel diameter across exercise intensities or between groups

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In fact, over the past decade hospitalizations due to NSAID-associated lower gut complications have increased compared to the upper gut pathologies [136], thereby underscoring the relevance of NSAID-enteropathy manifested as iron deficiency anemia, protein loss and hypoalbuminemia, indigestion, and abdominal pain