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Overall, 14 of 16 patients reported pain relief. Promising human signal? Yes. Proof that it works? Not without a legit randomized controlled trial. I would love to see a trial comparing the

Patient selection: Clinical trials exclude patients with significant psychiatric comorbidity, eating disorders, and medication non-compliance - populations that may respond less well in practice

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It has been reported that IL-13 expression is elevated under inflammatory conditions, such as in the colonic mucosa of UC and CD patients [139, 140], and that this elevation possibly contributes to intestinal barrier dysfunction