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They found that among 46 γ-glutamyl peptides, glutathione (γ-glutamyl-cysteinyl-glycine) and γ-glutamyl-valinyl-glycine (γ-Glu-Val-Gly) were very strong calcium-sensing receptor (CaSR) agonists that increased the kokumi flavor of chicken consommé and enhanced sweet, salty, and umami tastes independently when added to aqueous solutions of sucrose, NaCl, and MSG, respectively, in human sensory tests

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The Nuclear factor kappa B (NF-κB) and Signal Transducer and Activator of Transcription signaling pathways collectively regulate the M1/M2 phenotypic ratio 59