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In this specific cycle: 1️⃣ Hydrogen peroxide, a free radical and reactive oxygen species, is converted into water (harmless), and oxygen 2️⃣ Two molecules of reduced Glutathione [GSH (the “active antioxidant” form of glutathione)] are used by the Glutathione peroxidase enzyme to “neutralize” one molecule of hydrogen peroxide 3️⃣ NADPH is used by glutathione reductase enzyme to reduce ("recycle") glutathione disulfide back into usable reduced glutathione Key players: 🌟 Selenium: Essential for the enzyme that initiates the breakdown of hydrogen peroxide 🌟 Riboflavin (FAD - coenzyme form of riboflavin): essential for the enzyme that restores the oxidized Glutathione back to its more useful state