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For example, the human 15-LOX-2 isoform produces 13( S )-HpODE while the murine gene Alox15b encodes a 8( S )-LOX enzyme that forms 9( S )-HpODE from LA

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Up to 80% of cirrhosis patients report poor sleep quality, as evidenced by Pittsburgh Sleep Quality Index (PSQI) scores exceeding 5 (Child–Turcotte–Pugh [CTP] A: 16.9%, CTP B: 26.5%, and CTP C: 56.6%), and around 16 to 52% suffer from excessive daytime sleepiness (EDS), reflected by Epworth Sleepiness Scale (ESS) scores over 10 (CTP A: 17.6%, CTP B: 29.7%, CTP C: 52.8%) (31)

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