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In active acromegaly, many observations show that due to the high GH levels, glucose levels tend to be elevated, which is accompanied by the well-known high insulin levels in untreated acromegaly patients [33,34]

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For all ICRs, including ICRs where we did not propose changes to the number of respondents, responses, or time per response, the costs identified in the revised collection of information requests reflect the updated 2024 wage rate data described in section V.A