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Abbreviations : cav-1 Caveolin 1, DACD Low-Molecular-Mass Penicillin Binding Protein 6b, IL6 Interleukin 6, TNFα Tumor necrosis factor, PEBP1 Phosphatidylethanolamine binding protein 1, Nrf2 Nuclear factor erythroid 2–related factor 2, HO-1 Heme oxygenase-1, SOD2 Superoxide dismutase 2, ACSL4 Acyl-CoA Synthetase Long Chain Family Member 4, PEBP1 Phosphatidylethanolamine binding protein 1, GPX4 Glutathione Peroxidase 4, Aβ Amyloid beta, NLRP3 NLR Family Pyrin Domain Containing 3, DMT1 Natural resistance-associated macrophage protein 1, NCOA4 Nuclear receptor coactivator 4, TSG Tumor necrosis factor-α-stimulated gene/protein, ALXO5 Arachidonate 5-lipoxygenase, 5-HETE 5-Hydroxyeicosatetraenoic acid, MAO-B Monoamine oxidase B, KEAP1 Kelch-like ECH-associated protein 1 Alzheimer’s disease AD manifests as a catastrophic neurodegenerative disorder typified by the incremental loss of cognitive faculties, memory deterioration, and behavioral metamorphoses
