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Abstract Glutathione-mediated biotransformation in the liver is a well-known detoxification process to eliminate small xenobiotics, but its impacts on nanoparticle retention, targeting and clearance are much less understood than liver macrophage uptake, even though both processes are involved in liver detoxification

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Newer classes of insecticides are now coming onto the market place for vector control, but the high cost of developing and registering them inevitably means that insecticides are developed initially for the agricultural market and then utilized for public health vector control, where their activities and safety profile are appropriate