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9,29–36 Mediating processes include, hormesis (low dose beneficial stimulation rather than inhibition of adaptive function), 37–39 cross-adaptation (one stressor can initiate adaptive changes that improve or worsen resilience to an entirely different type of stressor), 40–46 and time-dependent sensitization (TDS) 10,47–49 (progressive endogenous response amplification over time, including cross-sensitized oscillation in direction of responses at physiological limits)

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Despite the controversial role of GPX7 in carcinogenesis 5,23 , there is limited literature on the potential mechanisms of GPX7 expression in gliomas