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Consistently, in obese women undergoing bariatric surgery, a short-term low-calorie diet (2 weeks) markedly reduced the adipose tissue expression of the inflammatory markers CD45 and CCL2 [147]

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Likely, it may bring the theory to practical application, starting with the initial argument, no degradation in human gastric juice for more than 24 h, and thereby, the therapeutic effectiveness (including via a therapeutic per-oral regimen) and pleiotropic beneficial effects