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Since VDZ selectively binds to the integrin ɑ 4 β 7 , blocking its interaction with MAdCAM-1, we then looked at the ratio of ɑ 4 β 7 + cells in the biopsies relative to the blood for each subset, and found that VDZ significantly decreased ɑ 4 β 7 + cells in colon biopsies in the majority (21 of 23) cell subsets to varying extents (Fig

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Lipopolysaccharide structures of gram-negative populations in the gut microbiota and effects on host interactions

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