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Facilitated by the peptide PTP targeting plectin-1 specifically overexpressed on the surface of pancreatic ductal adenocarcinoma cells and the peptide RGD binding to the integrin widely expressed on pancreatic duct epithelial cells and angiogenesis, the bispecific molecular probe has a clinical perspective with good retention, long cycle time, and excellent specificity

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GLP-1 medications, specifically semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), work in part by acting on receptors in the brain that regulate hunger