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GPX4 deficiency-dependent phospholipid peroxidation drives motor deficits of ALS - ScienceDirect

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Glutathione biosynthesis occurs in several, but not in all eukaryotic cell types through a well-coordinated and feedback-modulated process that needs one essential amino acid, cysteine, and two others, glutamic acid and glycine, that most cells can synthesize themselves from the intermediates of core metabolism