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Additionally, if you're taking vitamin B12, some medicines can interfere with your ability to digest it, including: Aminosalicylic acid (Paser), used to treat digestive problems Colchicine (Colcrys, Mitigare, Gloperba) is an anti-inflammatory medicine used to prevent and treat gout Proton pump inhibitors (Prilosec, Prevacid) are used to reduce stomach acid Metformin (Glumetza, Fortamet, others), used to treat diabetes Vitamin C supplements SLIDESHOW See Slideshow What are the warning signs of vitamin B12 deficiency